□ 개최배경
생물학적동등성시험 평가기술의 최신동향에 대한 국제 심포지움을 약제학회와 공동으로 개최하여 생동성시험의 국제적 추세에 대하여 공부하고, 우리 나라 제도의 개선 및 기술적 운영에 대한 토론의 장을 마련하고자 함.

□ 행사개요
○ 주제 : 개량신약 개발을 위한 DDS와 생물학적동등성 최신 연구
○ 일시 : 2003. 11. 27∼28 (2일간)
○ 장소 : 서울대학교 호암생활관 삼성컨벤션센터
○ 연자 : 국내·외 13명

□ 발표과제 및 내용
- Overview of BA/BE and regulations (Moo Kwang Park, National Institute of Health, U.S.A.)
- Use of FDA guidance and computer simulation to optimize BA/BE study outcomes focusing on sample size, sampling time and food effect (Young Ho Kim, GlaxoSmithKline Co., U.S.A.)
- Japanese perspective on PK, BE and BA (Naoko Kaniwa, National Iinstitute of Health Sciences, Japan)
- Time and state-varying pharmacokinetics and pharmacodynamics : Impact on rational dosing strategies (James A. Uchizono, University of the Pacific, U.S.A.)
- Targeting hypoxic cells in tumours: a PK/PD perspective
(William R. Wilson, Auckland Cancer Society Research Center, New Zealand)
- Regulation of the expression of the multidrug resistance transporter P-glycoprotein in multicellular prostate tumor spheroids by reactive oxygen species (Heinrich Sauer, Justus-Liebig-University Giessen, Germany)-첨부파일 없음
- Impact of chemoinfomatrical analysis to process analysis technology in pharmaceutical industry (Makoto Otsuka, Kobe Pharmaceutical University, Japan)
- Pharmacokinetic-pharmacodynamic modeling of fenofibrate in Korean population (Dong Chul Kim, Chungnam National University)
- Effects of intravenous infusion time and the rate and composition of fluid replacement on the pharmacokinetics and pharmacodynamics of the same total dose of torasemide (So Hee Kim, Kangnung National University)
- Involvement of rOCT2 in the saturable distribution of tacrine to the brain in rats (Suk-Jae Chung, Seoul National University)
- Disposition kinetics of risperidone in healthy Korean subjects in relation to the genetic polymorphism of CYP2D6 and MDR1 (Yong-Bok Lee, Chonnam National University)
- Current status of bioequivalence test and policy measures to increase bioequivalent pharmaceutical products (Eui Kyung Lee, Korea Institute for Health and Social Affairs)
- Current aspects of bioequivalence study (Soo Youn Chung, National Institute of Toxicological Research, KFDA)